Structure of PDB 6wrf Chain A

Receptor sequence
>6wrfA (length=351) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
LPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKS
NILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQ
KLLQKSDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLK
LIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVE
TGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVAT
LNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAM
ARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIDGQSEPLLIY
G
3D structure
PDB6wrf Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates.
ChainA
Resolution3.14 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y153 V154 T199 Y90 V91 T136
BS02 AGS A I79 G122 S123 G124 K125 T126 L127 A369 R370 I16 G59 S60 G61 K62 T63 L64 A306 R307
BS03 MG A T126 D184 T63 D121
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6wrf, PDBe:6wrf, PDBj:6wrf
PDBsum6wrf
PubMed33089779
UniProtP0A6H1|CLPX_ECOLI ATP-dependent Clp protease ATP-binding subunit ClpX (Gene Name=clpX)

[Back to BioLiP]