Structure of PDB 6wo2 Chain A

Receptor sequence
>6wo2A (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
EMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGN
DVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
V
3D structure
PDB6wo2 Some thermodynamic effects of varying nonpolar surfaces in protein-ligand interactions.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R67 R86 S88 S90 S96 Q106 H107 F108 K109 L120 W121 R14 R33 S35 S37 S43 Q53 H54 F55 K56 L67 W68
BS02 CA A H79 E152 H26 E99
External links
PDB RCSB:6wo2, PDBe:6wo2, PDBj:6wo2
PDBsum6wo2
PubMed32916312
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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