Structure of PDB 6wnl Chain A

Receptor sequence
>6wnlA (length=356) Species: 9606 (Homo sapiens) [Search protein sequence]
SFEGQMAEYPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLE
CLKVYLYCSPVTKELLLTSPKYRFWKKRIISIEIETPTQISLVDEASGEK
EEIVVTLLPAGHCPGSVMFLFQGNNGTVLYTGDFRLAQGEAARMELLHSG
GRVKDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVW
LNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMPEILHHLTTDRNTQI
HACRHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSTNVIV
RTGESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVIPVGTTMDKVVEIL
KPLCRS
3D structure
PDB6wnl Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features.
ChainA
Resolution2.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H228 H254 C256 C272 H225 H251 C253 C269
BS02 ZN A H33 H35 H115 D136 H31 H33 H112 D133
External links
PDB RCSB:6wnl, PDBe:6wnl, PDBj:6wnl
PDBsum6wnl
PubMed32576658
UniProtQ96SD1|DCR1C_HUMAN Protein artemis (Gene Name=DCLRE1C)

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