Structure of PDB 6wn8 Chain A

Receptor sequence
>6wn8A (length=209) Species: 72407 (Klebsiella pneumoniae subsp. pneumoniae) [Search protein sequence]
AMKIVEVKHPLVKHKLGLMREHDISTKRFRELASEVGSLLTYEATADLET
EKVTIEGWNGPVEVEQIKGKKITVVPILRAGLGMMEGVLEHVPSARISVV
GIYRNEETLEPVPYFQKLVSNIDERMALVVDPMLATGGSMIATIDLLKNA
GCTSIKVLVLVAAPEGIAALEKAHPDVELYTASVDKGLNEHGYIIPGLGD
AGDKIFGTK
3D structure
PDB6wn8 A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.9: uracil phosphoribosyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BDF A E5 K7 H8 E42 E6 K8 H9 E43
BS02 BDF A Y41 E42 Y42 E43
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004845 uracil phosphoribosyltransferase activity
GO:0005525 GTP binding
GO:0016757 glycosyltransferase activity
Biological Process
GO:0006223 uracil salvage
GO:0008655 pyrimidine-containing compound salvage
GO:0044206 UMP salvage

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:6wn8, PDBe:6wn8, PDBj:6wn8
PDBsum6wn8
PubMed36695589
UniProtA6TCB0|UPP_KLEP7 Uracil phosphoribosyltransferase (Gene Name=upp)

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