Structure of PDB 6wgv Chain A

Receptor sequence
>6wgvA (length=173) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
DGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLR
QIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPAL
KSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNR
LSDLLFILSRVANPDGDVLWRPG
3D structure
PDB6wgv Mobile loop dynamics in adenosyltransferase control binding and reactivity of coenzyme B 12 .
ChainA
Resolution2.151 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.17: corrinoid adenosyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 B12 A L114 K115 S116 F117 V118 R133 R137 S166 D167 F170 W184 L100 K101 S102 F103 V104 R119 R123 S152 D153 F156 W170
BS02 3PO A R137 N163 R123 N149
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008817 corrinoid adenosyltransferase activity
GO:0016740 transferase activity
Biological Process
GO:0006779 porphyrin-containing compound biosynthetic process
GO:0009236 cobalamin biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6wgv, PDBe:6wgv, PDBj:6wgv
PDBsum6wgv
PubMed33199623
UniProtP9WP99|PDUO_MYCTU Corrinoid adenosyltransferase (Gene Name=Rv1314c)

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