Structure of PDB 6we6 Chain A

Receptor sequence
>6we6A (length=405) Species: 303 (Pseudomonas putida) [Search protein sequence]
NLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESNVPDLVWTRCN
GGHWIATRGQLIREAYEDYRHFSSECPFIPREAGEAYDFIPTSMDPPEQR
QFRALANQVVGMPVVDKLENRIQELACSLIESLRPQGQCNFTEDYAEPFP
IRIFMLLAGLPEEDIPHLKYLTDQMTRPDGSMTFAEAKEALYDYLIPIIE
QRRQKPGTDAISIVANGQVNGRPITSDEAKRMCGLLLVGGLETVVNFLSF
SMEFLAKSPEHRQELIERPERIPAACEELLRRFSLVADGRILTSDYEFHG
VQLKKGDQILLPQMLSGLDERENAAPMHVDFSRQKVSHTTFGHGSHLCLG
QHLARREIIVTLKEWLTRIPDFSIAPGAQIQHKSGIVSGVQALPLVWDPA
TTKAV
3D structure
PDB6we6 Proton Relay Network in the Bacterial P450s: CYP101A1 and CYP101D1.
ChainA
Resolution2.16 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R186 E251 T252 C357 L358 G359
Catalytic site (residue number reindexed from 1) R177 E242 T243 C348 L349 G350
Enzyme Commision number 1.14.15.1: camphor 5-monooxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A T101 R112 L244 L245 T252 D297 R299 Q322 T349 F350 G351 H355 C357 T92 R103 L235 L236 T243 D288 R290 Q313 T340 F341 G342 H346 C348
BS02 CAM A Y96 V247 Y87 V238
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0018683 camphor 5-monooxygenase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0019383 (+)-camphor catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6we6, PDBe:6we6, PDBj:6we6
PDBsum6we6
PubMed32574066
UniProtP00183|CPXA_PSEPU Camphor 5-monooxygenase (Gene Name=camC)

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