Structure of PDB 6wcw Chain A

Receptor sequence
>6wcwA (length=247) Species: 9606 (Homo sapiens) [Search protein sequence]
NAQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYF
CQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDIN
SALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTED
LHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQN
EDDIIFPFELHKCRTCEECKACYHKACFKSGSCPRCERLQARREALA
3D structure
PDB6wcw Structural basis for autophagy inhibition by the human Rubicon-Rab7 complex.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C721 C724 C747 C750 C25 C28 C51 C54
BS02 ZN A C826 H877 C881 C130 H181 C185
BS03 ZN A C891 C894 H920 C923 C195 C198 H224 C227
BS04 ZN A C912 C929 C216 C233
External links
PDB RCSB:6wcw, PDBe:6wcw, PDBj:6wcw
PDBsum6wcw
PubMed32632011
UniProtQ92622|RUBIC_HUMAN Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Gene Name=RUBCN)

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