Structure of PDB 6w7e Chain A

Receptor sequence
>6w7eA (length=252) Species: 10090 (Mus musculus) [Search protein sequence]
KWKTVSTIFLVVVLYLIIGATVFKALEQPQEISQRTTIVIQREKFLRAHP
CVSDQELDELIQQIVAAINAGSHWDLGSSFFFAGTVITTIGFGNISPRTE
GGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKQTKIR
IISTIIFILFGCVLFVALPAVIFSALDAIYFVVITLTTIGFGDYVLDFYK
PVVWFWILVGLAYFAAVLSMIGDWLRVIAKKTKEAVGEFRAHAAEWTANV
TS
3D structure
PDB6w7e K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
ChainA
Resolution3.29 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 K A T142 I143 T251 I252 G253 T89 I90 T188 I189 G190
BS02 PIO A T46 R297 K301 K304 T4 R226 K230 K233
BS03 K A T142 T251 T89 T188
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6w7e, PDBe:6w7e, PDBj:6w7e
PDBsum6w7e
PubMed33127683
UniProtP97438|KCNK2_MOUSE Potassium channel subfamily K member 2 (Gene Name=Kcnk2)

[Back to BioLiP]