Structure of PDB 6w74 Chain A

Receptor sequence
>6w74A (length=87) Species: 9606 (Homo sapiens) [Search protein sequence]
MQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRC
WESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRY
3D structure
PDB6w74 Structural Characterization of BTK:PROTAC:cIAP Ternary Complexes: From Snapshots to Ensembles
ChainA
Resolution2.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C306 C309 H326 C333 C41 C44 H61 C68
BS02 TKY A D303 G312 L313 R314 C315 D320 E325 W329 D38 G47 L48 R49 C50 D55 E60 W64
External links
PDB RCSB:6w74, PDBe:6w74, PDBj:6w74
PDBsum6w74
PubMed
UniProtQ13490|BIRC2_HUMAN Baculoviral IAP repeat-containing protein 2 (Gene Name=BIRC2)

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