Structure of PDB 6w6j Chain A

Receptor sequence
>6w6jA (length=620) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
QALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEP
GVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMVAGSKYRGEFEER
LKAVLDDIKNSAGQIITFIDELHTIVGAGAAGNMIKPMLARGELRLVGAT
TLDEYRKHIEKDAALERRFQQVYVGEPSVEDTIGILRGLKDRYEVHHGVR
ITDSALVAAATLSDRYITARFLPDKAIDLVDEAASRLRMEIDSRPVEIDE
VERLVRRLEIEEMALSKEEDEASAERLAKLRSELADQKEKLAELTTRWQN
EKNAKEEVGPDDIADVVSAWTGIPAGRLLEGETAKLLRMEDELGKRVIGQ
KAAVTAVSDAVRRSRAGVSDPNRPTGAFMFLGPTGVGKTELAKALADFLF
DDERAMVRIDMSEYGEKHTVARLIGAPPGYVGYEAGGQLTEAVRRRPYTV
VLFDEIEKAHPDVFDVLLQVLDEGRLTDGHGRTVDFRNTILILTSNLGSG
GSAEQVLAAVRATFKPEFINRLDDVLIFEGLNPEELVRIVDIQLAQLGKR
LAQRRLQLQVSLPAKRWLAQRGFDPVYGARPLRRLVQQAIGDQLAKMLLA
GQVHDGDTVPVNVSPDADSL
3D structure
PDB6w6j Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K250 Y251 G654 Y655 V656 K92 Y93 G429 Y430 V431
BS02 AGS A G209 G211 K212 T213 I350 L354 G51 G53 K54 T55 I185 L189
BS03 AGS A I573 V611 G612 K613 T614 R805 I348 V386 G387 K388 T389 R580
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009408 response to heat
GO:0034605 cellular response to heat
GO:0042026 protein refolding
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w6j, PDBe:6w6j, PDBj:6w6j
PDBsum6w6j
PubMed34038719
UniProtP9WPD1|CLPB_MYCTU Chaperone protein ClpB (Gene Name=clpB)

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