Structure of PDB 6w4z Chain A

Receptor sequence
>6w4zA (length=152) Species: 9606 (Homo sapiens) [Search protein sequence]
LSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQN
GSSVKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKS
FEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFS
FS
3D structure
PDB6w4z Rational Design and Synthesis of Methyl-beta-d-galactomalonyl Phenyl Esters as Potent Galectin-8 N Antagonists.
ChainA
Resolution1.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SZS A R45 Q47 R59 H65 R69 W86 E89 Y141 R43 Q45 R57 H63 R67 W84 E87 Y139 MOAD: Kd=9.17uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:6w4z, PDBe:6w4z, PDBj:6w4z
PDBsum6w4z
PubMed32809817
UniProtO00214|LEG8_HUMAN Galectin-8 (Gene Name=LGALS8)

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