Structure of PDB 6w35 Chain A

Receptor sequence
>6w35A (length=792) Species: 9598 (Pan troglodytes) [Search protein sequence]
NISGSCKGRCFELQPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDR
CGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAEC
PAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYP
TKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGG
QPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFY
SEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFV
GDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKA
IIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARK
PLGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYKTKVPPFENIELYNVMC
DLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFD
LGCTCDDKNKLDELNKRLHTKGSTEERHLLYGRPAVLYRTRYDILYHTDF
ESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCL
AYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQR
VLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHY
YSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEE
LMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYE
3D structure
PDB6w35 Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry.
ChainA
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005044 scavenger receptor activity
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0030247 polysaccharide binding
GO:0046872 metal ion binding
Biological Process
GO:0006955 immune response
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005576 extracellular region
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w35, PDBe:6w35, PDBj:6w35
PDBsum6w35
PubMed32584034
UniProtK7CID1

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