Structure of PDB 6w12 Chain A

Receptor sequence
>6w12A (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]
SCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQ
KYLGSAYTWMGLSDPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGG
EDCAHFHPDGRWNDDVCQRPYHWVCEAGL
3D structure
PDB6w12 Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen.
ChainA
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A Q267 D269 E280 N292 D293 Q88 D90 E101 N113 D114
BS02 CA A V218 N220 E224 E305 V39 N41 E45 E126
BS03 CA A K264 H286 K85 H107
BS04 CA A D243 D270 E280 D281 D64 D91 E101 D102
External links
PDB RCSB:6w12, PDBe:6w12, PDBj:6w12
PDBsum6w12
PubMed33724805
UniProtQ8IUN9|CLC10_HUMAN C-type lectin domain family 10 member A (Gene Name=CLEC10A)

[Back to BioLiP]