Structure of PDB 6w04 Chain A

Receptor sequence
>6w04A (length=223) Species: 5759 (Entamoeba histolytica) [Search protein sequence]
MEAVLFDFNGTLIFDTPLHAFCWKEMAKRIRGTPLSEDEFKLLNGRTNKQ
LIEHILNKEISDEDAKKYAEEKENLYRTMLMKSDIKLCDGAINLFEALKK
CNIPFTIATSSDWGNVQVFIQKYHLEEWFDIDKIIFNDFTFKGKPAPDIY
LKASKKLGVSISHCIVFEDTISGIHSALSAGATPIGIASEMTVNELLQIK
GCNLAIHTFNEITIEEMVDLIKN
3D structure
PDB6w04 Crystal structure of HAD hydrolase, family IA, variant 3 from Entamoeba histolytica HM-1:IMSS
ChainA
Resolution1.95 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D7 F8 N9 D15 N44 T109 S110 K144 E168 D169
Catalytic site (residue number reindexed from 1) D7 F8 N9 D15 N44 T109 S110 K144 E168 D169
Enzyme Commision number 3.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D7 N9 D169 D7 N9 D169
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6w04, PDBe:6w04, PDBj:6w04
PDBsum6w04
PubMed
UniProtC4LXK0

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