Structure of PDB 6vzy Chain A

Receptor sequence
>6vzyA (length=464) Species: 285532 (Streptomyces achromogenes subsp. streptozoticus) [Search protein sequence]
SHMSHVPPHVPFELSGAELRDAIVQYATNPIYHDNLDWLNHDNPYRRQLR
PQVLPHLDYDKVPGRENILNYASLAVQRLLTSVYEADLVFFPKSGLKGKE
EDFRAFYSPANRALGERIRPALERYAFGFLDDEVGTWTAQSLDAYLDSLE
QSPVEKAILGSADRERAARMWLVQFAPDFLSEASPMMRNVLGYYGPAQSE
WFKVVIDEYGYGVHDTKHSTLFERTLESVGLESDLHRYWQYYLNSSLLLN
NYFHYLGKNHELFFRYVGALYYTESSLVDFCRRADHLLREVFGDTVDTTY
FTEHIHIDQHHGRMAREKIIKPLVEAHGDGIIPEIVRGIEEYRVLLEIGD
FDFSEQIAWMDAQPELKKLHDPVFEGLKQGKVDAPVAHLVEPRGELSNTH
CHDGDELCHIVSGTMRFESGLGSSLTLQAGEGVVIKRNRLHGANIESDEC
VYEIHSVGDYRKCL
3D structure
PDB6vzy Structure and assembly of the diiron cofactor in the heme-oxygenase-like domain of the N -nitrosourea-producing enzyme SznF.
ChainA
Resolution1.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.250: nitrosourea synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE2 A E189 E215 H225 H311 E182 E208 H218 H304
BS02 FE2 A E215 E281 D315 H318 E208 E274 D308 H311
BS03 FE2 A H407 H409 H448 H400 H402 H441
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0046872 metal ion binding
Biological Process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6vzy, PDBe:6vzy, PDBj:6vzy
PDBsum6vzy
PubMed33468680
UniProtA0A411MR89|SZNF_STRC2 Nitrosourea synthase (Gene Name=sznF)

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