Structure of PDB 6vvo Chain A

Receptor sequence
>6vvoA (length=448) Species: 9606 (Homo sapiens) [Search protein sequence]
KVENLLWVDKYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSDDGSSFK
AALLSGPPGVGKTTTASLVCQELGYSYVELNASDTRSKSSLKAIVAESLN
NTSIKGFYSNSVSTKHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPII
CMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIKGAMMSIAFKEGLKIPPPA
MNEIILGANQDIRQVLHNLSMWCARSKALMGPFDVARKVFAAGEETAHMS
LVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDMKKHLMLLSRAADSIC
DGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPSWLGKH
SSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVD
GVQDVVALMDTYYLMKEDFENIMEISSWGGKPSPFSKPKVKAAFTRAY
3D structure
PDB6vvo Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AGS A V587 P592 I598 I599 V655 G656 K657 T658 T659 N753 R812 V8 P13 I19 I20 V60 G61 K62 T63 T64 N154 R213
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
Cellular Component
GO:0005663 DNA replication factor C complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6vvo, PDBe:6vvo, PDBj:6vvo
PDBsum6vvo
PubMed
UniProtP35251|RFC1_HUMAN Replication factor C subunit 1 (Gene Name=RFC1)

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