Structure of PDB 6vtv Chain A

Receptor sequence
>6vtvA (length=249) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
NNPVIGVVMCRNRLKGHATQTLQEKYLNAIIHAGGLPIALPHALAEPSLL
EQLLPKLDGIYLPGSPSNVQPHLYGENGDEPDADPGRDLLSMAIINAALE
RRIPIFAICRGLQELVVATGGSLHRKLCEQPELLEHREDPELPVEQQYAP
SHEVQVEEGGLLSALLPECSNFWVNSLHGQGAKVVSPRLRVEARSPDGLV
EAVSVINHPFALGVQWHPEWNSSEYALSRILFEGFITACQHHIAEKQRL
3D structure
PDB6vtv PuuD gamma-glutamyl-gamma-aminobutyrate hydrolase
ChainA
Resolution2.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.94: gamma-glutamyl-gamma-aminobutyrate hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H145 H161 S185 H187 E210 H136 H152 S176 H178 E201
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0033969 gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Biological Process
GO:0006598 polyamine catabolic process
GO:0009447 putrescine catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6vtv, PDBe:6vtv, PDBj:6vtv
PDBsum6vtv
PubMed
UniProtP76038|PUUD_ECOLI Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (Gene Name=puuD)

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