Structure of PDB 6vou Chain A

Receptor sequence
>6vouA (length=176) Species: 588 (Providencia stuartii) [Search protein sequence]
GIEYRSLHTSQLTLSEKEALYDLLIEGFEGDFSHDDFAHTLGGMHVMAFD
QQKLVGHVAIIQRHMALDNTPISVGYVEAMVVEQSYRRQGIGRQLMLQTN
KIIASCYQLGLLSASDGQKLYHSVGWQIWKGKLFELKQGSYIRSIEEEGG
VMGWKADGEVDFTASLYCDFRGGDQW
3D structure
PDB6vou Structural basis for plazomicin antibiotic action and resistance.
ChainA
Resolution1.95 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.59: gentamicin 2'-N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A F29 M81 V82 V83 R88 R89 G91 G93 R94 A115 S116 K121 Y123 F28 M80 V81 V82 R87 R88 G90 G92 R93 A114 S115 K119 Y121
BS02 PZC A D32 D37 A80 M81 S114 E149 D176 W178 D31 D36 A79 M80 S113 E147 D174 W176
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0047921 aminoglycoside 2'-N-acetyltransferase activity
Biological Process
GO:0046677 response to antibiotic

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6vou, PDBe:6vou, PDBj:6vou
PDBsum6vou
PubMed34117352
UniProtQ52424|AAC2_PROST Aminoglycoside 2'-N-acetyltransferase (Gene Name=aac)

[Back to BioLiP]