Structure of PDB 6vll Chain A

Receptor sequence
>6vllA (length=182) Species: 655278 (Influenza A virus (A/Luxembourg/43/2009(H1N1))) [Search protein sequence]
LVPRGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAATCTHLE
VCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDY
KENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYT
LDEESRARIKTRLFTIRQEMASRSLWDSFRQS
3D structure
PDB6vll Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential.
ChainA
Resolution2.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 R3J A Y24 H41 E80 D108 E119 Y31 H48 E68 D96 E107
BS02 MN A E80 D108 E68 D96
BS03 MN A H41 D108 E119 I120 H48 D96 E107 I108
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function

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Biological Process
External links
PDB RCSB:6vll, PDBe:6vll, PDBj:6vll
PDBsum6vll
PubMed
UniProtC6H0Y9

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