Structure of PDB 6vlh Chain A

Receptor sequence
>6vlhA (length=137) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
SSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAGQETAYFLLKLAGR
WPVKTVHTDNGSNFTSTTVKAACEWAGIKQEFGIPSMNKELKKIIGQVRD
QAEHLKTAVQMAVFIHNKKRIGGYSAGERIVDIIATD
3D structure
PDB6vlh HIV Integrase core domain (IN) in complex with dimeric spanning inhibitor
ChainA
Resolution2.036 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 R2A A E87 Q95 E96 A98 T125 A128 A129 A169 E170 H171 K173 T174 M178 E32 Q38 E39 A41 T68 A71 A72 A102 E103 H104 K106 T107 M111
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6vlh, PDBe:6vlh, PDBj:6vlh
PDBsum6vlh
PubMed
UniProtF2WR39

[Back to BioLiP]