Structure of PDB 6vlc Chain A

Receptor sequence
>6vlcA (length=371) Species: 122587 (Neisseria meningitidis Z2491) [Search protein sequence]
MKVLTVFGTRPEAIKMAPVILELQKHNTITSKVCITAQHREMLDQVLSLF
EIKADYDLNIMKPNQSLQEITTNIISSLTDVLEDFKPDCVLVHGDTTTTF
AASLAAFYQKIPVGHIEAGLRTYNLYSPWPEEANRRLTSVLSQWHFAPTE
DSKNNLLSESIPSDKVIVTGNTVIDALMVSLEKLKITTIKKQMEQAFPFI
QDNSKVILITAHRRENHGEGIKNIGLSILELAKKYPTFSFVIPLHLNPNV
RKPIQDLLSSVHNVHLIEPQEYLPFVYLMSKSHIILSDSGGIQEEAPSLG
KPVLVLRDTTERPEAVAAGTVKLVGSETQNIIESFTQLIEYPEYYEKMAN
IENPYGIGNASKIIVETLLKN
3D structure
PDB6vlc Structural characterization of a nonhydrolyzing UDP-GlcNAc 2-epimerase from Neisseria meningitidis serogroup A.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.1.3.14: UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UD1 A R10 P11 E12 D95 E117 H212 Q270 Y272 F275 S289 G290 G291 E295 R312 R10 P11 E12 D95 E117 H212 Q270 Y272 F275 S289 G290 G291 E295 R312
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity
GO:0016853 isomerase activity
Biological Process
GO:0045227 capsule polysaccharide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6vlc, PDBe:6vlc, PDBj:6vlc
PDBsum6vlc
PubMed33135674
UniProtA0A0U1RGY0|SACA_NEIMA UDP-N-acetylglucosamine 2-epimerase (Gene Name=sacA)

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