Structure of PDB 6vii Chain A

Receptor sequence
>6viiA (length=183) Species: 10090 (Mus musculus) [Search protein sequence]
ASLDRVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDIRVHDYK
EGTPEEKTYYIELWDVGGSVGSAKSTRAVFYNSVNGIILVHDLTNKKSSQ
NLYRWSLEVLNRDQIPLLVIGTKLDQIHETKRHEVLIRTAFLAEDFNAEE
INLDCTNPRSSAAGSSNAVKLSRFFDKVIEKRY
3D structure
PDB6vii Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A S20 T38 S19 T37
BS02 GSP A S15 G16 G18 K19 S20 S21 P35 W37 T38 K148 D150 D179 C180 T181 S14 G15 G17 K18 S19 S20 P34 W36 T37 K123 D125 D154 C155 T156
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0001779 natural killer cell differentiation
GO:0030183 B cell differentiation
GO:0033077 T cell differentiation in thymus
GO:0046578 regulation of Ras protein signal transduction
GO:0050821 protein stabilization
GO:1903059 regulation of protein lipidation

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Molecular Function

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Biological Process
External links
PDB RCSB:6vii, PDBe:6vii, PDBj:6vii
PDBsum6vii
PubMed32220963
UniProtQ9D4V7|RABL3_MOUSE Rab-like protein 3 (Gene Name=Rabl3)

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