Structure of PDB 6via Chain A

Receptor sequence
>6viaA (length=176) Species: 266264 (Cupriavidus metallidurans CH34) [Search protein sequence]
RHMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRT
DYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQ
RPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPP
LFESFYASEDKRRCPHCGQVHPGRAA
3D structure
PDB6via Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens.
ChainA
Resolution1.591 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.13.11.6: 3-hydroxyanthranilate 3,4-dioxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE2 A C125 C128 C162 C165 C127 C130 C164 C167
BS02 FE A H51 E57 H95 H53 E59 H97
BS03 EAY A V41 H51 E57 F59 P97 R99 E110 V43 H53 E59 F61 P99 R101 E112
Gene Ontology
Molecular Function
GO:0000334 3-hydroxyanthranilate 3,4-dioxygenase activity
GO:0005506 iron ion binding
GO:0008198 ferrous iron binding
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0006569 tryptophan catabolic process
GO:0009435 NAD biosynthetic process
GO:0019363 pyridine nucleotide biosynthetic process
GO:0019805 quinolinate biosynthetic process
GO:0034354 'de novo' NAD biosynthetic process from tryptophan
GO:0043420 anthranilate metabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6via, PDBe:6via, PDBj:6via
PDBsum6via
PubMed32732435
UniProtQ1LCS4|3HAO_CUPMC 3-hydroxyanthranilate 3,4-dioxygenase (Gene Name=nbaC)

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