Structure of PDB 6vef Chain A

Receptor sequence
>6vefA (length=844) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
DTNVKQVKVLQLINAYRFRGHQHANLDPLGLYQQDKVADLDPSFHDLTEA
DFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITSTEEKRW
IQQRIESGRATFNSEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGDA
LIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAG
KHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSV
RARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTV
RIVINNQVGFTTSNPLDARSTPYMTDIGKMVQAPIFHVNADDPEAVAFVT
RLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQKIKKHPTPRKIYAD
KLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNH
EWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEK
LFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTY
TPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDF
ANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQ
LCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVS
SLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHD
VAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHF
REVIPFGASLRYAGRPASASPAVGHMSVHQKQQQDLVNDALNVE
3D structure
PDB6vef Cryo-EM Structure of Escherichia coli 2-oxoglutarate dehydrogenase E1 component sucA
ChainA
Resolution4.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.2.4.2: oxoglutarate dehydrogenase (succinyl-transferring).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A H313 R337 S530 F531 W533 R710 M711 H229 R253 S441 F442 W444 R621 M622
BS02 OAA A L659 Q685 F689 L570 Q596 F600
BS03 OAA A R261 D357 F394 R177 D273 F310
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0030976 thiamine pyrophosphate binding
GO:0042802 identical protein binding
Biological Process
GO:0006099 tricarboxylic acid cycle
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0045252 oxoglutarate dehydrogenase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6vef, PDBe:6vef, PDBj:6vef
PDBsum6vef
PubMed
UniProtP0AFG3|ODO1_ECOLI 2-oxoglutarate dehydrogenase E1 component (Gene Name=sucA)

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