Structure of PDB 6veb Chain A

Receptor sequence
>6vebA (length=451) Species: 59201 (Salmonella enterica subsp. enterica) [Search protein sequence]
MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLEAGARLTVNALTFIPQFT
VWANEGMLTLVEGPFDETLLDSCWLAIAATDDDTVNQRVSDAAESRRIFC
NVVDAPKAASFIMPSIIDRSPLMVAVSAGGTSPVLARLLREKLESLLPQH
LGQVARYAGQLRARVKKQFATMGERRRFWEKFFVNDRLAQSLANADEKAV
NATTERLFSEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADIVVYDRL
VSDDIMNLVRRDADRVFVGKVPQEEINQILLREAQKGKRVVRLKGGDPFI
FGRGGEELETLCHAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLV
TGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQEKLIAFGMQADMPVA
LVENGTSVKQRVVHGVLTQLGELAQQVESPALIIVGRVVALRDKLNWFSN
H
3D structure
PDB6veb Siroheme synthase orients substrates for dehydrogenase and chelatase activities in a common active site.
ChainA
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.1.76: precorrin-2 dehydrogenase.
2.1.1.107: uroporphyrinogen-III C-methyltransferase.
4.99.1.4: sirohydrochlorin ferrochelatase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0004325 ferrochelatase activity
GO:0004851 uroporphyrin-III C-methyltransferase activity
GO:0008168 methyltransferase activity
GO:0016491 oxidoreductase activity
GO:0016829 lyase activity
GO:0043115 precorrin-2 dehydrogenase activity
GO:0051266 sirohydrochlorin ferrochelatase activity
GO:0051287 NAD binding
Biological Process
GO:0006779 porphyrin-containing compound biosynthetic process
GO:0009236 cobalamin biosynthetic process
GO:0019354 siroheme biosynthetic process
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6veb, PDBe:6veb, PDBj:6veb
PDBsum6veb
PubMed32054833
UniProtP25924|CYSG_SALTY Siroheme synthase (Gene Name=cysG)

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