Structure of PDB 6vdc Chain A

Receptor sequence
>6vdcA (length=497) Species: 1772 (Mycolicibacterium smegmatis) [Search protein sequence]
GRALEPGELAAWLSEHSLGSRFGVAVVGTHKAYDADATALAIVAADGDGR
YIDTSTLTPEDEAALASWLADPGPPKALHEAKLAMHDLAGRGWTLRGVTS
DTALAAYLVRPGQRSFTLDDLAVRYLHRELRGVDEQAVQTVILRACAVLD
LADALDQELARIDSLSLLSRMELPVQRTLAEMEHAGIAVDLGMLEQLQSE
FADQIRDAPFLQHLLAHRDATRLKVTVDGLLNSVASDGRIHTTFNQTIAA
TGRLSSTEPNLQNIPIRTEAGRRIRDAFVVGEGYAELMTADYSQIEMRIM
AHLSRDAGLIEAFNTGEDLHSFVASRAFSVPEVTPELRRRVKAMSYGLAE
EAKVQMEQYFDRFGGVRDYLRDVVDQARKDGYTSTVLGRRRYLPELDSSN
RQVREAAERAALNAPIQGSAADIIKVAMINVDQAIKDAGLRSRILLQVHD
ELLFEVSEGEQGELEQLVREHMGNAYPLDVPLEVSVGYGRSWDAAAH
3D structure
PDB6vdc Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme.
ChainA
Resolution2.402 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H337 D367 D369 H16 D46 D48
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6vdc, PDBe:6vdc, PDBj:6vdc
PDBsum6vdc
PubMed32034423
UniProtA0QYZ2

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