Structure of PDB 6vcs Chain A

Receptor sequence
>6vcsA (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
PSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLA
GGYEDDVDHGNFFTYTGSGGQSCDQKLTNTNRALALNCFAPINDQEGAEA
KDWRSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFL
VWRYLLRRDDDEPGPWTKEGKDRIKKLGLTMQYPEGY
3D structure
PDB6vcs SRA domain of UHRF1 in complex with DNA
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A P414 S415 E438 R443 R452 P1 S2 E25 R30 R39
BS02 dna A R443 P444 H445 V446 A447 R30 P31 H32 V33 A34
External links
PDB RCSB:6vcs, PDBe:6vcs, PDBj:6vcs
PDBsum6vcs
PubMed
UniProtQ96T88|UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (Gene Name=UHRF1)

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