Structure of PDB 6vbz Chain A

Receptor sequence
>6vbzA (length=256) Species: 10116 (Rattus norvegicus) [Search protein sequence]
VKEIPKEDLGYPWTKLKTNKLSTIYRGEYYKSPVTIKVFNNPKAESVGIV
RLTFNEEIKTMKKFDSPNILRIFGICIDQTVKPPEFSIVMEYCELGTLRE
LLDRDKDLTMSVRSLLVLRAARGLYRLHHSGTLHGNISSSSFLVAGGYQV
KLAGFELSRFSSTAYVSPERLQDPFCKYDTKAEIYSFGIVLWEIATGKIP
FEGCDSEKIYELVAENKKQEPVGQDCPELLQEIINECRAHEPSNRPSADG
ILERLP
3D structure
PDB6vbz Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues.
ChainA
Resolution2.192 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N318 S322 S323 G336
Catalytic site (residue number reindexed from 1) N136 S140 S141 G154
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A E426 E430 E228 E232
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6vbz, PDBe:6vbz, PDBj:6vbz
PDBsum6vbz
PubMed32561735
UniProtD3ZKP6

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