Structure of PDB 6vbw Chain A

Receptor sequence

>6vbwA (length=450) Species: 666 (Vibrio cholerae) [Search protein sequence]

TTELKRAFRPLTPHINELDALTILVNLTDKAKCKQKLRDEKWWASCINCV
NYRQSHNPKFPDIRSEGVIRTQALGELPSFLLSSSKIPPYHWSYSHDSKY
VNKSAFLTNEISCLGKTCKAMAKQLADITLTTINVTLAPNYLTQISLPDS
DTSYISLSPVASLSMQSHFHQRLQDENRHSAITRFSRTTNMGVTAMTCGG
AFRMLKSGAKFSSPPHSFLVLPNIRVCGATALSSPVTVGIPSLTAFFGFV
HAFERNINRTTSSFRVESFAICVHQLHVEKRGLTAEFVETISAPATRDDW
QCDVVFSLILNTNFIDQDTLVTSLPKRLARGSAKIAIDDFKHINSFSTLE
TAIESLPIEAGRWLSLYAQSNNNLSDLLAAMTEDHQLMASCVGYHLLEEP
KDKPNSLRGYKHAIAECIIGLINSITFDPNTIFWSLKNYQNYLVVQPRSI

3D structure

PDB

6vbw Structure-function insights into the initial step of DNA integration by a CRISPR-Cas-Transposon complex.

Chain

Resolution

3.2 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	K49 S127 K128 N131 M252	K30 S98 K99 N102 M196
BS02	dna	A	K88 I92 D126 S127 K128 R243 N246	K59 I63 D97 S98 K99 R187 N190
BS03	rna	A	P90 T199 Q200 I201 S202 Y210 P215 V216 A217 P404 T413 H420 R424 L452 T453 A454 R503 A505 R506 Y570 R584	P61 T143 Q144 I145 S146 Y154 P159 V160 A161 P235 T244 H251 R255 L283 T284 A285 R327 A329 R330 Y394 R408

External links

PDB	RCSB:6vbw, PDBe:6vbw, PDBj:6vbw
PDBsum	6vbw
PubMed	31925391

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