Structure of PDB 6v2n Chain A

Receptor sequence
>6v2nA (length=518) Species: 562 (Escherichia coli) [Search protein sequence]
GLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGYERGVLTNLGAV
AVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETWQHL
KGLVTRQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRP
SDEELAGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGT
WYGGEMKKGMFSMMNYLLPLKGIASMHCSANVGEAGDVAVFFGLTLSTDP
ARRLIGDDEHGWDDDGVFNFEGGSYAKTIKLSKEAEPEIYAAIRRDALLE
NVTKRENGTIDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLT
ADAFGVLPPVSRLTADQTQYHFLSGFTAPTPTFSACFGAAFLSLHPTQYA
EVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGSLDNAET
FTLPMFNLAIPTELPGVDTGILDPRNTYASPEQWQEKAETLAKLFIDNFD
KYTDTPAGAALVAAGPAL
3D structure
PDB6v2n Kinetic and structural analysis of Escherichia coli phosphoenolpyruvate carboxykinase mutants.
ChainA
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R65 K213 H232 D269 R333
Catalytic site (residue number reindexed from 1) R60 K208 H227 D258 R322
Enzyme Commision number 4.1.1.49: phosphoenolpyruvate carboxykinase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A K213 H232 D269 K208 H227 D258
BS02 ACT A R65 Y207 K213 R60 Y202 K208
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004611 phosphoenolpyruvate carboxykinase activity
GO:0004612 phosphoenolpyruvate carboxykinase (ATP) activity
GO:0005509 calcium ion binding
GO:0005524 ATP binding
GO:0016831 carboxy-lyase activity
GO:0017076 purine nucleotide binding
GO:0046872 metal ion binding
Biological Process
GO:0006094 gluconeogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6v2n, PDBe:6v2n, PDBj:6v2n
PDBsum6v2n
PubMed31911238
UniProtP22259|PCKA_ECOLI Phosphoenolpyruvate carboxykinase (ATP) (Gene Name=pckA)

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