Structure of PDB 6v1l Chain A

Receptor sequence
>6v1lA (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
NPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLN
LPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPG
DDIVLMAEALEKLFLQKINELPT
3D structure
PDB6v1l Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5U6 A W81 P82 F83 L92 L94 N140 W38 P39 F40 L49 L51 N97 MOAD: Kd=418nM
BindingDB: IC50=>100000nM,Kd=>10000nM
External links
PDB RCSB:6v1l, PDBe:6v1l, PDBj:6v1l
PDBsum6v1l
PubMed32091206
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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