Structure of PDB 6v1k Chain A

Receptor sequence
>6v1kA (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTEE
3D structure
PDB6v1k Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5SW A W81 P82 Q85 V87 L92 L94 N140 W40 P41 Q44 V46 L51 L53 N99 BindingDB: IC50=>100000nM,Kd=>10000nM
External links
PDB RCSB:6v1k, PDBe:6v1k, PDBj:6v1k
PDBsum6v1k
PubMed32091206
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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