Structure of PDB 6v1f Chain A

Receptor sequence
>6v1fA (length=117) Species: 9606 (Homo sapiens) [Search protein sequence]
EQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTM
KEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKI
LSQERIQSLKQSIDFMA
3D structure
PDB6v1f Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5U6 A F155 F156 P159 I164 N211 Y217 F24 F25 P28 I33 N80 Y86 MOAD: Kd=418nM
BindingDB: IC50=3410nM,Kd=418nM
External links
PDB RCSB:6v1f, PDBe:6v1f, PDBj:6v1f
PDBsum6v1f
PubMed32091206
UniProtQ9NPI1|BRD7_HUMAN Bromodomain-containing protein 7 (Gene Name=BRD7)

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