Structure of PDB 6v1e Chain A

Receptor sequence
>6v1eA (length=119) Species: 9606 (Homo sapiens) [Search protein sequence]
EQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTM
KEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKI
LSQERIQSLKQSIDFMADL
3D structure
PDB6v1e Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
ChainA
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5SW A F155 F156 F158 V160 I164 N211 Y217 F24 F25 F27 V29 I33 N80 Y86 MOAD: Kd=121nM
BindingDB: IC50=117nM,Kd=0.316228nM
External links
PDB RCSB:6v1e, PDBe:6v1e, PDBj:6v1e
PDBsum6v1e
PubMed32091206
UniProtQ9NPI1|BRD7_HUMAN Bromodomain-containing protein 7 (Gene Name=BRD7)

[Back to BioLiP]