Structure of PDB 6v16 Chain A

Receptor sequence
>6v16A (length=118) Species: 9606 (Homo sapiens) [Search protein sequence]
EQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTM
KEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKI
LSQERIQSLKQSIDFMAD
3D structure
PDB6v16 Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QMG A F155 V160 I164 N211 Y217 F24 V29 I33 N80 Y86 MOAD: Kd=556nM
BindingDB: Kd=556nM
BS02 QMG A R236 S239 R105 S108 MOAD: Kd=556nM
BindingDB: Kd=556nM
External links
PDB RCSB:6v16, PDBe:6v16, PDBj:6v16
PDBsum6v16
PubMed32091206
UniProtQ9NPI1|BRD7_HUMAN Bromodomain-containing protein 7 (Gene Name=BRD7)

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