Structure of PDB 6v14 Chain A

Receptor sequence
>6v14A (length=102) Species: 9606 (Homo sapiens) [Search protein sequence]
STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMK
DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM
SK
3D structure
PDB6v14 Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QMG A F160 F163 V165 I169 N216 Y222 F23 F26 V28 I32 N79 Y85 MOAD: Kd=82nM
BindingDB: Kd=33nM
External links
PDB RCSB:6v14, PDBe:6v14, PDBj:6v14
PDBsum6v14
PubMed32091206
UniProtQ9H8M2|BRD9_HUMAN Bromodomain-containing protein 9 (Gene Name=BRD9)

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