Structure of PDB 6v0x Chain A

Receptor sequence
>6v0xA (length=99) Species: 9606 (Homo sapiens) [Search protein sequence]
STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMK
DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKM
3D structure
PDB6v0x Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 B49 A F160 F161 V165 I169 Y173 N216 Y222 F23 F24 V28 I32 Y36 N79 Y85 MOAD: Kd=277uM
BindingDB: Kd=17000nM
External links
PDB RCSB:6v0x, PDBe:6v0x, PDBj:6v0x
PDBsum6v0x
PubMed32091206
UniProtQ9H8M2|BRD9_HUMAN Bromodomain-containing protein 9 (Gene Name=BRD9)

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