Structure of PDB 6v0t Chain A

Receptor sequence
>6v0tA (length=402) Species: 9913 (Bos taurus) [Search protein sequence]
TPPQVNSILKANEYSFKVPEFDGKNVSSVLGFDSNQLPANAPIEDRRSAA
TCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAV
ESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNIDVKEAL
INAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHV
ANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNEREVERLKLEHPKNEAKS
VVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPKFIPPNYYTPPYL
TAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMDQNAA
THLIRHAVGNNEFGAERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGA
YQ
3D structure
PDB6v0t Crystal structure of the catalytic subunit of bovine pyruvate dehydrogenase phosphatase.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.43: [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D73 G74 D64 G65
BS02 MN A D73 D347 D445 D64 D323 D384
BS03 MN A H410 H414 H352 H356
BS04 MN A S290 I291 P321 S275 I276 P297
Gene Ontology
Molecular Function
GO:0004722 protein serine/threonine phosphatase activity
GO:0043169 cation binding
Biological Process
GO:0006470 protein dephosphorylation

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6v0t, PDBe:6v0t, PDBj:6v0t
PDBsum6v0t
PubMed32627744
UniProtP35816|PDP1_BOVIN [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (Gene Name=PDP1)

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