Structure of PDB 6v0a Chain A

Receptor sequence

>6v0aA (length=443) Species: 398767 (Trichlorobacter lovleyi SZ)

IPDGTIDPAVWGKNYPEEYQTWKDTALPTPEGKSKYKKGNDGGKVYDKLS
EYPFIALLFNGWGFGIEYNEPRGHVYMMKDQKEIDPSRLKGGGACLTCKT
PYAPQLAQKQGVTYFSQSYADAVNQIPKEHQEMGVACIDCHNNKDMGLKI
SRGFTLVKALDKMGVDQTLTNQDKRSLVCAQCHVTYTIPKDANMKSQDVF
FPWDESKWGKISIENIIKKMRSDKSYGEWTQAVTGFKMAYIRHPEFEMYS
NQSVHWMAGVSCADCHMPYTVGSKKISDHRIMSPLKNDFGCKQCHSESSE
WLKNQVITIQDRAASQYIRSGYALATVAKLFEMTHKQQAAGKQIDQKMYD
QAKFYYEEGFYRNLFFGAENSIGFHNPTEAMRILGDATMYAGKADGLLRQ
ALTKAGVDVPVKIDLELSKYTNNRGAKKLMFKPEQELKDPYGP

3D structure

• PDB: 6v0a Cytochromecnitrite reductase from the bacteriumGeobacter lovleyirepresents a new NrfA subclass.
• Chain: A
• Resolution: 2.55 Å

Enzymatic activity

• Enzyme Commision number: 1.7.2.2: nitrite reductase (cytochrome; ammonia-forming).

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEC	A	N103 Q115 I118 R122 C129 C132 K133 C217 H218 Y221 H278 N407	N69 Q81 I84 R88 C95 C98 K99 C182 H183 Y186 H243 N370
BS02	HEC	A	Y49 E52 Y53 W56 A170 C171 C174 H175 M180 L182 R210 M302 K311 I312 S313 H315	Y15 E18 Y19 W22 A136 C137 C140 H141 M146 L148 R175 M267 K275 I276 S277 H279
BS03	HEC	A	P105 R106 G107 H108 Y110 M111 D114 C132 C214 C217 H218 H301 I317	P71 R72 G73 H74 Y76 M77 D80 C98 C179 C182 H183 H266 I281
BS04	HEC	A	S68 K71 H218 Y284 H290 C297 C300 H301 S319 P320 Q347 N407 F411 H412	S34 K37 H183 Y249 H255 C262 C265 H266 S283 P284 Q310 N370 F374 H375
BS05	HEC	A	V289 H290 V295 C300 P320 C328 C331 H332 F411	V254 H255 V260 C265 P284 C291 C294 H295 F374
BS06	HEC	A	H332 E334	H295 E297

Gene Ontology

Molecular Function

• GO:0042279 nitrite reductase (cytochrome, ammonia-forming) activity

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:6v0a, PDBe:6v0a, PDBj:6v0a
• PDBsum: 6v0a
• PubMed: 32518164
• UniProt: B3E641