Structure of PDB 6uvm Chain A

Receptor sequence
>6uvmA (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTEE
3D structure
PDB6uvm Evaluating the Advantages of Using 3D-Enriched Fragments for Targeting BET Bromodomains.
ChainA
Resolution1.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QJA A W81 P82 L94 N140 I146 W40 P41 L53 N99 I105 MOAD: Kd=510uM
External links
PDB RCSB:6uvm, PDBe:6uvm, PDBj:6uvm
PDBsum6uvm
PubMed31857841
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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