Structure of PDB 6uvj Chain A

Receptor sequence
>6uvjA (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTEE
3D structure
PDB6uvj Evaluating the Advantages of Using 3D-Enriched Fragments for Targeting BET Bromodomains.
ChainA
Resolution1.38 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QJ1 A W81 P82 F83 L94 N140 I146 W40 P41 F42 L53 N99 I105 MOAD: Kd=20uM
BindingDB: Kd=20000nM
External links
PDB RCSB:6uvj, PDBe:6uvj, PDBj:6uvj
PDBsum6uvj
PubMed31857841
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

[Back to BioLiP]