Structure of PDB 6usu Chain A

Receptor sequence
>6usuA (length=274) Species: 10116 (Rattus norvegicus) [Search protein sequence]
RLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNDGSPRH
TVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVKKEWNGMMG
ELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKTRITGINDP
RLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQA
VRDNKLHAFIWDSAVLEFEASQCDLVTTGELFFRSGFGIGMRKDSPWKQN
VSLSILKSHENGFMEDLDKTWVRY
3D structure
PDB6usu Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
ChainA
Resolution2.092 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 QGM A Q13 F16 F92 P124 T126 R131 S179 S180 W223 D224 F250 Q9 F12 F85 P113 T115 R120 S167 S168 W211 D212 F237 BindingDB: Ki=6.3nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:6usu, PDBe:6usu, PDBj:6usu
PDBsum6usu
PubMed32610085
UniProtP35439|NMDZ1_RAT Glutamate receptor ionotropic, NMDA 1 (Gene Name=Grin1)

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