Structure of PDB 6upe Chain A

Receptor sequence
>6upeA (length=246) Species: 216597 (Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344) [Search protein sequence]
MAEPLTVSPELTANYAYFFDLDGTLAEIKPHPDQVVVPHKILQLLDRLAA
HNAGALALISGRSMTELDALAKPFRFPLAGVHGAERRDINGKTHIVRLPE
AVVREVEALLRSTLVALPGTELESKGMAFALHYRQAPEHEAALLALAQHV
TQHWPQLALQLGKCVVEIKPKGTNKGEAIAAFMQEAPFAGRIPVFVGDDL
TDEAGFGVVNHAGGISVKVGVGATQAAWRLESVPDVWRWLEQINYP
3D structure
PDB6upe Structural Analysis of Binding Determinants ofSalmonella typhimuriumTrehalose-6-phosphate Phosphatase Using Ground-State Complexes.
ChainA
Resolution2.244 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.12: trehalose-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D20 D202 D20 D202
BS02 OGS A D20 L21 D22 I28 P32 S60 G61 K125 H132 R134 K163 C164 D20 L21 D22 I28 P32 S60 G61 K125 H132 R134 K163 C164 MOAD: Ki=56uM
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004805 trehalose-phosphatase activity
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0005992 trehalose biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6upe, PDBe:6upe, PDBj:6upe
PDBsum6upe
PubMed32786412
UniProtE1WGG9|OTSB_SALTS Trehalose-phosphate phosphatase (Gene Name=otsB)

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