Structure of PDB 6up4 Chain A

Receptor sequence
>6up4A (length=814) Species: 10090 (Mus musculus) [Search protein sequence]
KSYIDRDTEYLLQENEPNLSLDQHLLEDLQRKKTDPRYIEMQRFRKKLPS
YGMQKELVNLINNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRI
VCTQPRRISAISVAERVATERAESCGNGNSTGYQIRLQSRLPRKQGSILY
CTTGIILQWLQSDSRLSSVSHIVLDEIHERNLQSDVLMTVIKDLLHFRSD
LKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDIIEKIRYVP
DQKQFKRGFMQGHVNRQEKEEKEAIYKERWPAYIKELRTRYSASTVDVLQ
MMDDDKVDLNLIAALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVM
FKSDKFLIIPLQTQVFKKTPPGVRKIVIATNIAETSITIDDVVYVIDGGK
IKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRAS
LLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVVLSI
KHLMELSALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTI
AASLSFKDPFVIPLGKEKIADARRKELAKETRSDHLTVVNAFEGWEEAKR
RGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRSPKDPKA
NINSDNEKIIKAVICAGLYPKVAKIRLNLKMVKVHTKSDGLVSIHPKSVN
VEQTDFHYNWLIYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQKDKDQ
EIIAVDEWIVFQSPERIAHLVKGLRKELDSLLQEKIESPHPVDWDDTKSR
DCAVLSAILDLIKT
3D structure
PDB6up4 Function of Auxiliary Domains of the DEAH/RHA Helicase DHX36 in RNA Remodeling.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A T224 G225 C226 G227 K228 T229 T230 R267 F529 T551 D553 T73 G74 C75 G76 K77 T78 T79 R116 F366 T388 D390
BS02 MG A T229 E327 T78 E176
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6up4, PDBe:6up4, PDBj:6up4
PDBsum6up4
PubMed32087197
UniProtQ8VHK9|DHX36_MOUSE ATP-dependent DNA/RNA helicase DHX36 (Gene Name=Dhx36)

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