Structure of PDB 6unc Chain A

Receptor sequence
>6uncA (length=278) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
GAEPTLWAISDLHTGHLGNKPVAESLYPSSPDDWLIVAGDVAERTDEIRW
SLDLLRRRFAKVIWVPGNHELWTTNRDPMQIFGRARYDYLVNMCDEMGVV
TPEHPFPVWTERGGPATIVPMFLLYDYSFLPEGANSKAEGVAIAKERNVV
ATDEFLLSPEPYPTRDAWCHERVAATRARLEQLDWMQPTVLVNHFPLLRQ
PCDALFYPEFSLWCGTTKTADWHTRYNAVCSVYGHLHIPRTTWYDGVRFE
EVSVGYPREWRRRKPYSWLRQVLPDPQY
3D structure
PDB6unc Structural insights into phosphopantetheinyl hydrolase PptH from Mycobacterium tuberculosis.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.14: [acyl-carrier-protein] phosphodiesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D25 H27 D54 H251 D11 H13 D40 H237
BS02 FE A D54 N82 H208 H249 D40 N68 H194 H235
Gene Ontology
Molecular Function
GO:0008770 [acyl-carrier-protein] phosphodiesterase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6unc, PDBe:6unc, PDBj:6unc
PDBsum6unc
PubMed31886928
UniProtI6YEE1|PPTH_MYCTU [Acyl-carrier-protein] phosphodiesterase PptH (Gene Name=pptH)

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