Structure of PDB 6ujk Chain A

Receptor sequence
>6ujkA (length=246) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
HMKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVVVDLRGDDVVGGLGDR
ARFAQADVTDEAAVSNALELADSLGPVRVVVNCAGTGNAIRVLSRDGVFP
LAAFRKIVDINLVGTFNVLRLGAERIAKTEPIGEERGVIINTASVAAFDG
QIGQAAYSASKGGVVGMTLPIARDLASKLIRVVTIAPGLFDTPLLAAKAS
LGQQVPHPSRLGNPDEYGALVLHIIENPMLNGEVIRLDGAIRMAPR
3D structure
PDB6ujk Crystal Structure of a Probable short-chain type dehydrogenase/reductase (Rv1144) from Mycobacterium tuberculosis with bound NAD
ChainA
Resolution1.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A G12 S15 G16 L17 D36 L37 D56 V57 C82 A83 T141 S143 Y156 K160 G187 F189 T191 L193 G13 S16 G17 L18 D37 L38 D57 V58 C83 A84 T142 S144 Y157 K161 G188 F190 T192 L194
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Cellular Component
External links
PDB RCSB:6ujk, PDBe:6ujk, PDBj:6ujk
PDBsum6ujk
PubMed
UniProtP9WGQ7|Y1144_MYCTU Uncharacterized oxidoreductase Rv1144 (Gene Name=Rv1144)

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