Structure of PDB 6uej Chain A

Receptor sequence
>6uejA (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
ADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVV
LEITRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSNLCKYSHE
VLSEENFKVLKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQI
CNQCSRLHICDHFTRGNCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQN
IQDICNSKHMQK
3D structure
PDB6uej Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences.
ChainA
Resolution2.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A R74 C88 K89 L90 Y98 K107 Y108 F144 R67 C81 K82 L83 Y91 K96 Y97 F133
BS02 ZN A C73 C78 C82 H86 C66 C71 C75 H79
BS03 ZN A C88 C96 C106 H110 C81 C89 C95 H99
BS04 ZN A C174 C182 C187 H191 C160 C168 C173 H177
BS05 ZN A C150 C162 H172 C139 C151 H158
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6uej, PDBe:6uej, PDBj:6uej
PDBsum6uej
PubMed31719195
UniProtQ7Z2W4|ZCCHV_HUMAN Zinc finger CCCH-type antiviral protein 1 (Gene Name=ZC3HAV1)

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