Structure of PDB 6u8i Chain A

Receptor sequence
>6u8iA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
SEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDM
STIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVF
EMRFAKMPD
3D structure
PDB6u8i Cyclic peptides can engage a single binding pocket through highly divergent modes.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W374 P375 F376 K378 L385 L387 H437 E438 W24 P25 F26 K28 L35 L37 H87 E88
External links
PDB RCSB:6u8i, PDBe:6u8i, PDBj:6u8i
PDBsum6u8i
PubMed33046654
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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