Structure of PDB 6u8h Chain A

Receptor sequence
>6u8hA (length=128) Species: 9606 (Homo sapiens) [Search protein sequence]
GSEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPD
YHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDI
VLMAQTLEKIFLQKVASMPQEEQELVVT
3D structure
PDB6u8h Cyclic peptides can engage a single binding pocket through highly divergent modes.
ChainA
Resolution2.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W97 P98 F99 Q101 V103 L108 L110 N156 I162 W35 P36 F37 Q39 V41 L46 L48 N94 I100
External links
PDB RCSB:6u8h, PDBe:6u8h, PDBj:6u8h
PDBsum6u8h
PubMed33046654
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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