Structure of PDB 6u7k Chain A

Receptor sequence
>6u7kA (length=1064) Species: 229032 (Porcine epidemic diarrhea virus CV777) [Search protein sequence]
APAVVVLGGYLPSVHGIFLSVGITWDNDRVTVFADKIYHFYLKNAMQYVY
TPTYYMLNVTSAGIYYEPCTANCTGYAANVFATDSNGHIPEGFSFNNWFL
LSNDSTLLHGKVVSNQPLLVNCLLAIPKIYGLGQFFSFNHTMDGVCNGAA
VDRAPEALRFNINDTSVILAEGSIVLHTALGTNLSFVCSNSSDPHLATEV
PYYCFLKVDTYNSTVYKFLAVLPPTVREIVITKYGDVYVNGFGYLHLGLL
DAVTINFTGHGTDDDVSGFWTIASTNFVDALIEVQGTSIQRILYCDDPVS
QLKCSQVAFDLDDGFYPISSRNLLSHEQPISFVTLPSFNDHSFVNITVSA
AFGGLSSANLVASDTTINGFSSFCVDTRQFTITLFYNVTNSYGYVSKSQD
SNCPFTLQSVNDYLSFSKFCVSTSLLAGACTIDLFGYPAFGSGVKLTSLY
FQFTKGELITGTPKPLEGITDVSFMTLDVCTKYTIYGFKGEGIITLTNSS
ILAGVYYTSDSGQLLAFKNVTSGAVYSVTPCSFSEQAAYVNDDIVGVISS
LSNSTFNNTRELPGFFYHSNDGSNCTEPVLVYSNIGVCKSGSIGYVPSQY
GQVKIAPTVTGNISIPTNFSMSIRTEYLQLYNTPVSVDCATYVCNGNSRC
KQLLTQYTAACKTIESALQLSARLESVEVNSMLTISEEALQLATISSFNG
DGYNFTNVLGAKRSVIEDLLFNKVVTNGLGTVDEDYKRCSNGRSVADLVC
AQYYSGVMVLPGVVDAEKLHMYSASLIGGMALGGITAAAALPFSYAVQAR
LNYLALQTDVLQRNQQLLAESFNSAIGNITSAFESVKEAISQTSKGLNTV
AHALTKVQEVVNSQGSALNQLTVQLQHNFQAISSSIDDIYSRLDILSADV
QVDRLITGRLSALNAFVAQTLTKYTEVQASRKLAQQKVNECVKSQSQRYG
FCGGDGEHIFSLVQAAPQGLLFLHTVLVPGDFVNVLAIAGLCVNGEIALT
LREPGLVLFTHELQTYTATEYFVSSRRMFEPRKPTVSDFVQIESCVVTYV
NLTSDQLPDVIPDY
3D structure
PDB6u7k The 3.1-Angstrom Cryo-electron Microscopy Structure of the Porcine Epidemic Diarrhea Virus Spike Protein in the Prefusion Conformation.
ChainA
Resolution3.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN A R311 E314 K399 R153 E156 K233
Gene Ontology
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046813 receptor-mediated virion attachment to host cell
GO:0075509 endocytosis involved in viral entry into host cell
Cellular Component
GO:0016020 membrane
GO:0019031 viral envelope
GO:0055036 virion membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6u7k, PDBe:6u7k, PDBj:6u7k
PDBsum6u7k
PubMed31534041
UniProtQ91AV1|SPIKE_PEDV7 Spike glycoprotein (Gene Name=S)

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